Index
| Substansgruppe(r) |
Antiepileptika
|
| Salgsnavn |
Zonegran |
| ATC-kode |
N03AX15
|
| CAS-nummer |
68291-97-4 |
| Molekylvekt |
212,23 |
| Biotilgjengelighet |
100 % |
| Tmax |
2-6 |
| Proteinbinding |
38-40 % |
| Distribusjonsvolum |
1,2-1,8 liter/kg |
| Blod/plasma-ratio |
4-5 |
| Halveringstid |
63±14 timer |
| Referanseområde |
45 –
180
μmol/L
|
Referanser
Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition
Randall Baselt: Disposition of toxic drugs and chemicals in man. Tenth edition
Statens legemiddelverk. Preparatomtale (SPC) Zonegran
Wikipedia
Sills G, Brodie M. Pharmacokinetics and drug interactions with zonisamide. Epilepsia 2007; 48(3): 435-41.
Mimaki T. Clinical pharmacology and therapeutic drug monitoring of zonisamide. Ther Drug Monit 1998; 20(6):593-7.
Sist oppdatert 01. oktober 2018
Tilgjengelige analyser
Plasma/Serum
Fullblod
